Histological and Biological Effects of Some Soft Drinks on Male Albino Rats

Document Type : Original Article

Authors

1 Nutrition & Food Science Dept., Faculty of Home Economics, Minoufia University, Shebin EL-Kom

2 Zoology Department, Faculty of Science, Suez University, Suez, Egypt

Abstract

sodas that could have a caloric or noncaloric sweetener. Several studies showed that the excessive consumption of soft drinks leads to harmful health effects. This study aimed to determine the effects of some soft drinks on the public health by examining the histological structure of the kidney, body weight, biochemical values, bone mineral density (BMD ) and bone Xray. Twenty male rats, (weighing 140 ±5 g), were divided into 4 groups. ; Group 1 (the control group) fed only on basal diet. ; Group 2 received a cola diet soft drink; Group 3 received an orange soft drink and Group 4 received a lemon soda soft drink. For histopathological examination, The kidneys were removed. The bone mineral density of the rats was assessed using Dual-energy X-ray absorptiometry (DXA). The body weight change and blood values were also determined. The histological examination of the kidneys showed general glomerular congestion, vacuolation, intertubular bleeding, tubular necrosis and hypotrophy of glomeruli. The weight gain was higher in the groups consuming diet drinks than the control group and the other group rats. There was a significant decrease in the bone mineral density of test groups when compared to the control group.

Keywords

Files

Share

How to cite

Statistics