Heliomycin (1) was isolated from the culture broth of actinomycete AB5. The structure of the isolated compound (1) was characterized by spectroscopic methods including NMR and mass spectrometry data. The influence of cultural parameters affecting the production of biomass including different culture media, pH values, temperatures, and incubation periods was investigated. The maximum production of secondary metabolites (2.78 g/l) was found in the culture medium of Waksman at initial pH 7.5 for four days at 35ºC. The antimicrobial activity of heliomycin (1) was evaluated against Gram-positive bacteria, Gram-negative bacteria, and fungi.
Mahmoud, A., Essawy, E., Abdalla, M., & Abdelfattah, M. (2019). Production of Heliomycin from Actinomycete and Evaluation of its Antimicrobial Activities. Journal of Bioscience and Applied Research, 5(4), 429-436. doi: 10.21608/jbaar.2019.114535
MLA
Abdulla A. Mahmoud; Ehab A. Essawy; Mohga S. Abdalla; Mohamed S. Abdelfattah. "Production of Heliomycin from Actinomycete and Evaluation of its Antimicrobial Activities". Journal of Bioscience and Applied Research, 5, 4, 2019, 429-436. doi: 10.21608/jbaar.2019.114535
HARVARD
Mahmoud, A., Essawy, E., Abdalla, M., Abdelfattah, M. (2019). 'Production of Heliomycin from Actinomycete and Evaluation of its Antimicrobial Activities', Journal of Bioscience and Applied Research, 5(4), pp. 429-436. doi: 10.21608/jbaar.2019.114535
VANCOUVER
Mahmoud, A., Essawy, E., Abdalla, M., Abdelfattah, M. Production of Heliomycin from Actinomycete and Evaluation of its Antimicrobial Activities. Journal of Bioscience and Applied Research, 2019; 5(4): 429-436. doi: 10.21608/jbaar.2019.114535
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