Histopathological study of thyroid carcinoma in Misan province

Document Type : Original Article

Authors

1 Histology / Basic Medical Science Department / Nursing College / Misan University, Iraq

2 Toxopathology / Basic Medical Science Department / Nursing College / Misan University, Iraq

3 Histology /Biology Department /College of Education for Pure Sciences /Wasit University, Iraq

Abstract

Aims: "Thyroid carcinoma is specific malignant tumors derived from follicle cells including papillary and follicular carcinoma, and parafollicular, calcitonin-producing C-cells (medullary carcinoma)".This study aimed to provide a present outlook on thyroid carcinoma among patients and investigation the relationship between the age, sex, and thyroid carcinoma in Missan province in Iraq. Methods: The data were collected in the period (First June – 2020 to Thirty November -2020) from (42) patients aged between (35 -80 or more) infected with thyroid carcinoma, a histopathological examination that performed and confirmed in the tissue sample obtained from the patients after surgical operations in AL-Sadder hospital in Missan province. Results: "The patients with thyroid carcinoma observed high incidence in ages between (41-55) years (42.8 %) cases, followed by the ages between (56-70) years (28.5 %) cases, while the lowest incidence observed in ages between (71or more )years (11.9%)cases. Thyroid carcinoma is observed more commonly found in females (64.28%) cases than the males (35.71%) cases (P < 0.05). Histopathological examination of the tissue specimens shows the commonest type of thyroid carcinoma was the papillary carcinoma" 28(66.6) cases characterized by multifocal with papillary architecture, changes in the size of thyrocytes with an abnormal nucleus and cytoplasm and shape, followed by follicular carcinomas 9(21.4) cases characterized by presence malignant epithelial cells arising from follicular cells and invasion into surrounding thyroid tissue, while the lowest type was Medullary carcinoma  5(11.9)cases, showing islands of tumor cells with central necrosis surrounded by vascular strom. Conclusion: "Papillary carcinoma is the most common malignant tumor of the thyroid gland and as compared with follicular carcinomas and medullary carcinoma. Proper implementation of preventive measures such as changing lifestyle factors might enhance control of thyroid carcinoma".

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