Study of the inhibitory effect of carnation plant Syzgium aromaticum on the growth of pathogenic fungus Candida albicans

Document Type : Original Article

Authors

1 Department of Biology, Collage of Science, University of Mosul, Iraq

2 Department of Biology, Collage of Education for Girls, University of Mosul, Iraq

3 Department of Community Health Techniques, Mosul Medical Technical Institute, Northern Technical University, Iraq

Abstract

Samples were taken from people wearing dentures to investigate the presence of fungal isolates belonging to the genus Candida, which were diagnosed through a direct examination using crystal violet stain and the germ tube formation test was then conducted to identify the isolates belonging to Candida albicans. The Dalma technique was used to confirm the diagnosis. The effect of the antibiotic Nystatin on Candida albicans isolates was tested, and the minimum inhibitory concentration was determined. The IU5000 concentration achieved the highest percentage of inhibition. The effect of some washes used by denture wearers, such as water and salt water, was also tested, and the sodium hypochlorite solution at 1% was the best in inhibiting Candida albicans, with 90-100% percentage inhibition. Subsequently, the minimum inhibitory effect of the aqueous and alcoholic extracts of cloves on Candida albicans isolates was studied, which showed that the aqueous and alcoholic extracts of cloves at 15 and 50 mg/ml, respectively, achieved the best percentage of inhibition with 80-90%.

Keywords

Journal of Bioscience and Applied Research
Volume 10, Issue 6 - Serial Number 6
Special issue; SPBH-IC: Biomedical
December 2024
Pages 180-194

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