Characterization, Antioxidant, and Anticancer activities of Silver Nanoparticles using Serenoa repens

Document Type : Original Article

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Department of Chemistry, College of Science, University of Thi-Qar, Thi-Qar, 64001, Iraq.

Abstract

Using the aqueous extracts from Serenoa repens fruits, silver nanoparticles (Ag NPs) have been synthesized simply, cheaply, and eco-friendly. Human prostate cancer antioxidant activity, as well as AgNP toxicity, were evaluated. The aqueous extract has been utilized as a reducing and stabilizing agent in a case when making AgNPs, which had been characterized with the use of a variety of methods, including ultraviolet-visible spectroscopy (UV-Vis), energy-dispersive X-ray (EDX), scanning electron microscopy (SEM), and Fourier transform infrared (FTIR). In the UV-Vis spectrum, the aqueous medium that contains AgNPs had shown an absorption peak at about 350nm. FTIR spectra showed that biomolecules have been responsible for capping and reduction agents of Ag NPs. The EDX spectrum indicates the presence of silver. Additionally, antioxidant activity has been assessed using the DPPH test. The percentage inhibition values concerning ascorbic acid, Serenoa repend extract, and AgNPs at 100 μg/mL were found to be 72.68, 80.08, and 75.3 μg/mL, respectively. It was discovered that NPs could stop large prostate cancer cells from growing.

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